Natural therapeutics

Cannabis is the oldest and most versatile medicine known to man.

Rare 11-leafer Cannabis sativa

Endocannabinoid receptors and endocannabinoids

Main article in wikipedia Endocannabinoid system

Human cells may have either of 2 types of endocannabinoid receptors CB₁ and CB₂. These receptors are present also in cells far away from the brain.

Anandamide, an endogenous ligand of CB₁ and CB₂

Endocannabinoids are produced by our own bodies the main ones being Anandamide and 2-AG.

Anandamide

• Anandamide was discovered in 1992. The name comes from the Sanskrit word 'Ananda' meaning 'bliss' and amide from its chemistry.

2-AG

• 2-AG was discovered in 1994-1995.

Links about 2-AG

• Herb.co article on 2-AG

N-Arachidonoyl dopamine

• N-Arachidonoyl dopamine discovered in 2000.

2-Arachidonyl glyceryl ether

• 2-Arachidonyl glyceryl ether discovered in 2001.

Virodhamine

• Virodhamine discovered in 2002

Lysophosphatidylinositol

• Lysophosphatidylinositol is a contender to be the 6th endocannabinoid.

Cannabis

A lovely female Cannabis indica. These are often good for pain relief producing a nice body stone.

Male Cannabis sativa plants in late blooming stage.

Cannabis sativa and Cannabis indica are the main cannabis variants though most strains are mixes of these. A third cannabis line is the Cannabis ruderalis, a rugged nothern cannabis that has adapted to flower even under northern long summer days.

Phytocannabinoids

Many people may know the 2 most prevalent phytocannabinoids, THC and CBD.

Full list of known phytocannabinoids from Wikipedia:

• THC (Tetrahydrocannabinol)
• THCA (Tetrahydrocannbinolic acid)
• CBD (Cannabidiol)
• CBDA (Cannabidiolic Acid)
• CBN (Cannabinol)
• CBG (Cannabigerol)
• CBC (Cannabichromene)
• CBL (Cannabicyclol)
• CBV (Cannabivarin)
• THCV (Tetrahydrocannabivarin)
• CBDV (Cannabidivarin)
• CBCV (Cannabichromevarin)
• CBGV (Cannabigerovarin)
• CBGM (Cannabigerol Monomethyl Ether)
• CBE (Cannabielsoin)
• CBT (Cannabicitran)

THC

Tetrahydrocannabinol

Tetrahydrocannabinol is the psychoactive compound that brings the 'high' most recreational users are chasing.

THCA

THC is produced from the raw THCA by a process called de-carboxylation. Basically means to heat the stuff over certain temperature.

CBD

Cannabidiol has the most medical applications of all phytocannabinoids.

CBDA

Cannabidiolic Acid is the raw form. Decarboxylating CBDA yields CBD.

• http://herb.co/2017/05/20/cbda/

CBN

Cannabinol

CBG

Cannabigerol

CBC

Cannabichromene

CBL

Cannabicyclol

CBV

Cannabivarin

THCV

Tetrahydrocannabivarin

CBDV

Cannabidivarin

CBCV

Cannabichromevarin

CBGV

Cannabigerovarin

CBGM

Cannabigerol Monomethyl Ether

CBE

Cannabielsoin

CBT

Cannabicitran

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Treating somatic issues

Cannabis can be applied to treat a wide assortment of illnesses. In this case it is called medical cannabis.

Due to the inbuilt default to always take the safe route and also to backup the back of your fellow MD colleague the Wikipedia does not yield the right infos on how useful and versatile a medication cannabis is.

Research has been held back by arcane laws even as cannabis is the oldest medicine known to man and it should be gladly appreciated and not outlawed because of big pharma interests.

Phytocannabinoid treatment of cancers

Full extract cannabis oil in a syringe for easy dosing and travel is usually administered in drops to the gums or under the tongue.

Internet is rife with stories about winning the battle against cancer with the help of phytocannabinoids. What does the science say?

4 points how cannabis works against cancer compiled by herb.co

1. Anti-proliferative - cannabis is against tumor growth
2. Anti-metastatic - cannabis is against cancer spreading to other parts in the body because of metastatic activity
3. Anti-angiogenetic - cannabis is against new blood vein growth to tumor
4. Apoptotic - cannabis causes cancer cells to programmedly kill themselves via Apoptosis.

Phytocannabinoids are harmless to healthy cannabinoid receptor containing cells.

Links about cannabis and cancer

• http://www.calgarycmmc.com/c.htm index into studies about the health benefits of cannabis, letter 'c' lists cancers for which studies have been done.
• http://www.umm.edu/programs/cancer/healthinfo/overviews/for-patients/cannabis-and-cannabinoids

Additionally anecdotally true are

1. Cannabis works very well against the somatic and nonsomatic pains brought on by cancer
2. Cannabis can help maintain a good appetite, chemo or no chemo.

Videos on the Internet about phytocannabinoid treatment of cancers

• Dr. Cristina Sanchez interview where she expains how apoptosis makes cancer cells kill themselves (a molecular biology research scientist who did her doctorates on exocannabinoids and cancers)
• Dr. Cristina Sanchez on how cannabinoids work against cancers
• Dr. Cristina Sanchez at Cannafest Prague 2015
• Dr. Cristina Sanchez lecture in Australia (no slideshow shots, sorry)

Leukemia

There are 2 main types of Leukemia:

• Myeloid leukemia (of the bone marrow)
• Lymphoid leukemia (of the lymphatic node)

Links about Lymphoid leukemia and cannabis

• https://ocgreenrelief.org/medical-marijuana/cannabis-oil-acute-leukemia-2
• http://truemedmd.com/2014/06/cannabis-oil-acute-leukemia/

Links about Myeloid leukemia and cannabis

• http://www.leafscience.com/2013/10/14/cannabinoids-destroy-leukemia-cells-new-study-finds/
• https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-2029-8 treating leukemia with w:Dronabinol (synthetic THC medication)
• http://www.healthmj.com/cancer/donavon-vizina-on-treating-acute-myeloid-leukemia-with-cannabis-oil/

Pain treatment

“You just don't feel like thinking about the pain.”

~ Apotheker Jukeboksi on somatic pain relief with cannabis

“There is more to it than that.”

~ Science on above quote

Epilepsy

Cannabis can be used to treat epilepsy.

• http://sorendreier.com/boy-with-100-seizures-a-day-now-has-none-after-taking-cannabis-oil/

Treating non-somatic issues

Cannabis can help with various non-somatic problems such as psychiatry, depression and PTSD.

External links

• http://www.calgarycmmc.com/ a large compendium on medical cannabis sorted alphabetically by ailment.
• http://www.encod.org/info/700-MEDICINAL-USES-OF-CANNABIS.html
• http://expand-your-consciousness.com/100-scientific-studies-agree-cannabis-annihilates-cancer/ about 100 nig.gov studies linked some cases briefly described.