Natural therapeutics: Difference between revisions
(THC image caption: Tetrahydrocannabinol is a partial w:agonist of CB<sub>1</sub> located mainly in the w:central nervous system, and the [[w:Cannabinoid receptor type 2|CB<sub>2</sub>]) |
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[[File:Cannabidiol.svg|thumb|right|200px|[[w:Cannabidiol|Cannabidiol]] ( | [[File:Cannabidiol.svg|thumb|right|200px|[[w:Cannabidiol|Cannabidiol]] has very low [[w:affinity (pharmacology)|affinity]] for the [[w:cannabinoid receptor|cannabinoid]] [[w:Cannabinoid receptor type 1|CB<sub>1</sub>]] and [[w:Cannabinoid receptor type 2|CB<sub>2</sub>]] receptors receptors but acts as an indirect [[w:receptor antagonist|antagonist]] of these receptors.]] | ||
[[w:Cannabidiol|Cannabidiol]] has the most medical applications of all phytocannabinoids. | [[w:Cannabidiol|Cannabidiol]] has the most medical applications of all phytocannabinoids. | ||
Revision as of 11:41, 17 July 2017
![](https://upload.wikimedia.org/wikipedia/commons/7/77/Cannabis_indica.jpg)
Cannabis is the oldest and most versatile medicine known to man.
Cannabis sativa and Cannabis indica are the main cannabis variants though most strains are mixes of these. A third cannabis line is the Cannabis ruderalis, a rugged nothern cannabis that has adapted to flower even under northern long summer days.
Endocannabinoid receptors
Main article in wikipedia Endocannabinoid system
Human body contains 2 types of endocannabinoid receptors CB1 and CB2.
CB1 receptors predominantly located in the nervous system, connective tissues, gonads, glands, and organs and [1]
CB2 receptors, primarily found in the immune system and also present in the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs. [1]
Endocannabinoids
Endocannabinoids are produced by our own bodies from Arachidonic acid or Omega-6 fatty acid[2].
The two main endocannabinoids are Anandamide and 2-AG.
Anandamide
Anandamide was discovered in 1992 and it binds to both CB1 and CB2 receptors. The name comes from the Sanskrit word 'Ananda' meaning 'bliss' and amide from its chemistry.
It has been referred to as the endocannabinoid version of THC.
2-AG
.
2-AG was discovered in 1994-1995.
Links about 2-AG
N-Arachidonoyl dopamine
N-Arachidonoyl dopamine discovered in 2000.
2-Arachidonyl glyceryl ether
2-Arachidonyl glyceryl ether discovered in 2001.
Virodhamine
Virodhamine discovered in 2002
Lysophosphatidylinositol
Lysophosphatidylinositol is a contender to be the 6th endocannabinoid.
Phytocannabinoids
![](https://upload.wikimedia.org/wikipedia/commons/thumb/4/48/Marijuana.jpg/420px-Marijuana.jpg)
Many people may know the 2 most prevalent phytocannabinoids, THC and CBD.
Full list of known phytocannabinoids from Wikipedia:
- THC (Tetrahydrocannabinol)
- THCA (Tetrahydrocannbinolic acid)
- CBD (Cannabidiol)
- CBDA (Cannabidiolic Acid)
- CBN (Cannabinol)
- CBG (Cannabigerol)
- CBC (Cannabichromene)
- CBL (Cannabicyclol)
- CBV (Cannabivarin)
- THCV (Tetrahydrocannabivarin)
- CBDV (Cannabidivarin)
- CBCV (Cannabichromevarin)
- CBGV (Cannabigerovarin)
- CBGM (Cannabigerol Monomethyl Ether)
- CBE (Cannabielsoin)
- CBT (Cannabicitran)
THC
![](https://upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Tetrahydrocannabinol.svg/200px-Tetrahydrocannabinol.svg.png)
Tetrahydrocannabinol is the psychoactive compound that brings the 'high' most recreational users are chasing.
THCA
THCA is the what cannabis plants produce to fend of insects from harming it. In pure form THCA is a clear translucent crystalline of white color.
THC is produced from the raw THCA by a process called decarboxylation. Basically means to heat the stuff over certain temperature.
THCA found in raw marijuana apparently has some health enhancing properties. The issue is being researched.
CBD
![](https://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Cannabidiol.svg/200px-Cannabidiol.svg.png)
Cannabidiol has the most medical applications of all phytocannabinoids.
CBDA
Cannabidiolic Acid is the raw form. Decarboxylating CBDA yields CBD.
CBN
CBG
CBC
CBL
CBV
THCV
CBDV
CBCV
Cannabichromevarin
CBGV
Cannabigerovarin
CBGM
Cannabigerol Monomethyl Ether
CBE
Cannabielsoin
CBT
Cannabicitran
Treating somatic issues
Cannabis can be applied to treat a wide assortment of illnesses. In this case it is called medical cannabis.
Due to the inbuilt default to always take the safe route and also to backup the back of your fellow MD colleague the Wikipedia does not yield the right infos on how useful and versatile a medication cannabis is.
Research has been held back by arcane laws even as cannabis is the oldest medicine known to man and it should be gladly appreciated and not outlawed because of big pharma interests.
Pain treatment
“You just don't feel like thinking about the pain.”
“There is more to it than that.”
Cannabis is anti-inflammatory which helps relieve some of the pain.
Epilepsy
Cannabis can be used to treat epilepsy.
Asthma
Amyotrophic lateral sclerosis
Cannabis helps with Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig's disease and motor neurone disease (MND).
Autoimmune diseases
Cannabis helps with many autoimmune diseases.
Links about autoimmune diseases and cannabis
Rheumatoid arthritis
Cannabis helps with Rheumatoid arthritis.
Links about Rheumatoid arthritis and cannabis
Lupus
Cannabis helps with Systemic lupus erythematosus
Coeliac disease
Cannabis helps with Coeliac disease.
Psoriasis
Cannabis helps with Psoriasis when applied externally.
Type 1 diabetes
Multiple sclerosis
Cannabis is very good against Multiple sclerosis.
Cancers
Internet is rife with stories about winning the battle against cancer with the help of phytocannabinoids. What does the science say?
- Anti-proliferative - cannabis is against tumor growth [3]
- Anti-metastatic - cannabis is against cancer spreading to other parts in the body because of metastatic activity[3]
- Anti-angiogenetic - cannabis is against new blood vein growth to tumor[3]
- Apoptotic - cannabis causes cancer cells to programmedly kill themselves via Apoptosis. [3]
- Pain relief - cannabis works very well against the somatic and nonsomatic pains brought on by cancer.
- Appetite stimulator - cannabis helps maintain a good appetite.
- Anti-nauseatic - cannabis helps with the chemotherapy-induced nausea and vomiting. [4] if you receive chemotherapy.
Phytocannabinoids are harmless to healthy cannabinoid receptor containing cells.
Studies about cannabis and cancer
Testimonies about cannabis and cancer
Links about cannabis and cancer
- http://www.calgarycmmc.com/c.htm index into studies about the health benefits of cannabis, letter 'c' lists cancers for which studies have been done.
- https://www.exposingtruth.com/123-cannabis-cancer/
Videos on the Internet about phytocannabinoid treatment of cancers
Cristina Sánchez is one of the foremost researchers into the anti-cancer qualities of cannabinoids of our time.
- Dr. Cristina Sanchez interview where she expains how apoptosis makes cancer cells kill themselves (a molecular biology research scientist who did her doctorates on exocannabinoids and cancers)
- Dr. Cristina Sanchez on how cannabinoids work against cancers
- Dr. Cristina Sanchez at Cannafest Prague 2015
- Dr. Cristina Sanchez lecture in Australia (no slideshow shots, sorry)
Leukemia
There are 2 main types of Leukemia:
- Myeloid leukemia (of the bone marrow)
- Lymphoid leukemia (of the lymphatic node)
Links about Lympoid and Myeloid leukemia and cannabis
Links about Lymphoid leukemia and cannabis
- https://ocgreenrelief.org/medical-marijuana/cannabis-oil-acute-leukemia-2
- http://truemedmd.com/2014/06/cannabis-oil-acute-leukemia/
Links about Myeloid leukemia and cannabis
- http://www.leafscience.com/2013/10/14/cannabinoids-destroy-leukemia-cells-new-study-finds/
- http://www.healthmj.com/cancer/donavon-vizina-on-treating-acute-myeloid-leukemia-with-cannabis-oil/
Prostate cancer
Cannabis helps with prostate cancer.
- herb.co/2017/01/13/prostate-cancer-cannabis/
Treating non-somatic issues
Cannabis can help with various non-somatic problems such as psychiatry, depression and PTSD.
External links
- http://www.calgarycmmc.com/ a large compendium on medical cannabis sorted alphabetically by ailment.
- http://www.encod.org/info/700-MEDICINAL-USES-OF-CANNABIS.html
- http://expand-your-consciousness.com/100-scientific-studies-agree-cannabis-annihilates-cancer/ about 100 nig.gov studies linked some cases briefly described.
References
- ↑ 1.0 1.1 https://patients4medicalmarijuana.wordpress.com/2017/07/06/how-and-why-your-brain-makes-its-own-cannabinoids/
- ↑ https://wakeup-world.com/2014/09/08/the-endocannabinoid-system-and-how-thc-cures-cancer/
- ↑ 3.0 3.1 3.2 3.3 http://herb.co/2016/08/25/cannabis-kills-cancer/
- ↑ http://herb.co/2017/01/03/cannabis-chemotherapy-induced-nausea/